Our paper studying the evolution of cancer cell organotropism using a zebrafish xenograft model is now in press at Cell Systems! I am particularly excited about the use of zebrafish systems to interrogate dynamic events in vivo. Thanks to all of the coauthors on the paper - the variety of techniques that we were able to bring to this study greatly enhanced the work.
Congratulations to Dr. Rory Staunton, Dr. Woong Young So, and Dr. Kandice Tanner on the publication of our paper studying cell mechanics in 3D! The study found that malignant breast cancer cells are mechanically plastic and are stiffer than the local microenvironment when cultured in 3D. In contrast, nonmalignant cells more closely match the mechanics of the local ECM. The study can be found here.
|
AuthorColin Paul is a CRTA Fellow at the National Cancer Institute, National Institutes of Health. Archives
August 2019
Categories |